230418006: Lennox-Gastaut syndrome (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Head finding (finding)\Finding of brain\Seizure\Seizure disorder\Epilepsy\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome
\Head finding (finding)\Finding of brain\Disorder of brain (disorder)\Seizure disorder\Epilepsy\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome
\Head finding (finding)\Disorder of head (disorder)\Disorder of brain (disorder)\Seizure disorder\Epilepsy\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome

\Central nervous system finding\Finding of brain\Seizure\Seizure disorder\Epilepsy\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome
\Central nervous system finding\Finding of brain\Disorder of brain (disorder)\Seizure disorder\Epilepsy\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome
\Central nervous system finding\Disorder of the central nervous system (disorder)\Disorder of brain (disorder)\Seizure disorder\Epilepsy\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome

\Neurological finding\Seizure related finding\Seizure\Seizure disorder\Epilepsy\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome

\Disease\Disorder of body system\Disorder of nervous system (disorder)\Disorder of the central nervous system (disorder)\Disorder of brain (disorder)\Seizure disorder\Epilepsy\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome
\Disease\Disorder of head (disorder)\Disorder of brain (disorder)\Seizure disorder\Epilepsy\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome
\Disease\Developmental disorder\Neurodevelopmental disorder\Developmental and epileptic encephalopathy\Lennox-Gastaut syndrome

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

345281011 Lennox-Gastaut syndrome en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core
618222015 Lennox-Gastaut syndrome (disorder) en Fully specified name Active Entire term case sensitive (core metadata concept) SNOMED CT core
5373042017 LGS - Lennox-Gastaut syndrome en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core
5464931017 A type of developmental and epileptic encephalopathy that presents with drug-resistant seizures between 18 months and 18 years of age (peak onset at 3 to 5 years, onset in second decade is rare). Tonic seizures and at least one other seizure type are mandatory for the diagnosis. Other seizure types include atypical absence seizures, atonic seizures, myoclonic seizures, focal seizures, generalised tonic-clonic seizures, nonconvulsive status epilepticus and epileptic spasms. Development is usually impaired before seizure onset, but over time there is developmental slowing and plateauing with subsequent moderate to severe intellectual disability in 90% of individuals. Behaviour disorders (hyperactivity, aggression), autism spectrum disorder, sleep disturbances are common. Neurological examination is often abnormal and related to the underlying aetiology. The EEG has diffuse background slowing. Interictal generalised slow spike-and-wave (≤2.5 Hz) and generalised paroxysmal fast activity in sleep (10 Hz or more) are mandatory diagnostic criteria. en Definition Active Entire term case sensitive (core metadata concept) SNOMED CT core
5464932012 A type of developmental and epileptic encephalopathy that presents with drug-resistant seizures between 18 months and 18 years of age (peak onset at 3 to 5 years, onset in second decade is rare). Tonic seizures and at least one other seizure type are mandatory for the diagnosis. Other seizure types include atypical absence seizures, atonic seizures, myoclonic seizures, focal seizures, generalized tonic-clonic seizures, nonconvulsive status epilepticus and epileptic spasms. Development is usually impaired before seizure onset, but over time there is developmental slowing and plateauing with subsequent moderate to severe intellectual disability in 90% of individuals. Behavior disorders (hyperactivity, aggression), autism spectrum disorder, sleep disturbances are common. Neurological examination is often abnormal and related to the underlying etiology. The EEG has diffuse background slowing. Interictal generalized slow spike-and-wave (≤2.5 Hz) and generalized paroxysmal fast activity in sleep (10 Hz or more) are mandatory diagnostic criteria. en Definition Active Entire term case sensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Lennox-Gastaut syndrome	Is a	Cryptogenic generalized epilepsy	false	Inferred relationship	Some
Lennox-Gastaut syndrome	Finding site	Cerebrum	false	Inferred relationship	Some	1
Lennox-Gastaut syndrome	Has definitional manifestation	Seizure	false	Inferred relationship	Some
Lennox-Gastaut syndrome	Is a	Epileptic encephalopathy (disorder)	false	Inferred relationship	Some
Lennox-Gastaut syndrome	Pathological process (attribute)	Pathological developmental process	true	Inferred relationship	Some	2
Lennox-Gastaut syndrome	Finding site	Brain structure	true	Inferred relationship	Some	2
Lennox-Gastaut syndrome	Is a	Developmental and epileptic encephalopathy	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Cryptogenic Lennox-Gastaut syndrome	Is a	False	Lennox-Gastaut syndrome	Inferred relationship	Some
Symptomatic Lennox-Gastaut syndrome	Is a	False	Lennox-Gastaut syndrome	Inferred relationship	Some

Reference Sets

Component annotation with string value reference set (foundation metadata concept)

Back to Start

Id	Description	Lang	Type	Status	Case?	Module
345281011	Lennox-Gastaut syndrome	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
618222015	Lennox-Gastaut syndrome (disorder)	en	Fully specified name	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
5373042017	LGS - Lennox-Gastaut syndrome	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
5464931017	A type of developmental and epileptic encephalopathy that presents with drug-resistant seizures between 18 months and 18 years of age (peak onset at 3 to 5 years, onset in second decade is rare). Tonic seizures and at least one other seizure type are mandatory for the diagnosis. Other seizure types include atypical absence seizures, atonic seizures, myoclonic seizures, focal seizures, generalised tonic-clonic seizures, nonconvulsive status epilepticus and epileptic spasms. Development is usually impaired before seizure onset, but over time there is developmental slowing and plateauing with subsequent moderate to severe intellectual disability in 90% of individuals. Behaviour disorders (hyperactivity, aggression), autism spectrum disorder, sleep disturbances are common. Neurological examination is often abnormal and related to the underlying aetiology. The EEG has diffuse background slowing. Interictal generalised slow spike-and-wave (≤2.5 Hz) and generalised paroxysmal fast activity in sleep (10 Hz or more) are mandatory diagnostic criteria.	en	Definition	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
5464932012	A type of developmental and epileptic encephalopathy that presents with drug-resistant seizures between 18 months and 18 years of age (peak onset at 3 to 5 years, onset in second decade is rare). Tonic seizures and at least one other seizure type are mandatory for the diagnosis. Other seizure types include atypical absence seizures, atonic seizures, myoclonic seizures, focal seizures, generalized tonic-clonic seizures, nonconvulsive status epilepticus and epileptic spasms. Development is usually impaired before seizure onset, but over time there is developmental slowing and plateauing with subsequent moderate to severe intellectual disability in 90% of individuals. Behavior disorders (hyperactivity, aggression), autism spectrum disorder, sleep disturbances are common. Neurological examination is often abnormal and related to the underlying etiology. The EEG has diffuse background slowing. Interictal generalized slow spike-and-wave (≤2.5 Hz) and generalized paroxysmal fast activity in sleep (10 Hz or more) are mandatory diagnostic criteria.	en	Definition	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core