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900000000000508004: Great Britain English language reference set (foundation metadata concept)


Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT model component module (core metadata concept)

Descriptions:

Id Description Lang Type Status Case? Module
900000000001112010 Great Britain English language reference set en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT model component module (core metadata concept)
900000000001113017 GB English en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT model component module (core metadata concept)
900000000001114011 Great Britain English language reference set (foundation metadata concept) en Fully specified name Active Entire term case sensitive (core metadata concept) SNOMED CT model component module (core metadata concept)


1342375 members. Search Members:

Expanded Value Set


Outbound Relationships Type Target Active Characteristic Refinability Group Values
GB English Is a English [International Organization for Standardization 639-1 code en] language reference set (foundation metadata concept) true Inferred relationship Some

Members acceptabilityId
A solid single-dose form that is a shell made of gelatin or other substances. The contents of the shell may be a solid, semi-solid or liquid. Preferred (foundation metadata concept)
A solid single-dose form that is a single layer or multilayer sheet of suitable material(s) intended to disperse rapidly. Preferred (foundation metadata concept)
A solid single-dose form that is a wafer enclosing a unit dose. Preferred (foundation metadata concept)
A solid single-dose form that is flexible and intended to be applied to a body surface to release the active substance(s) over a period of time. Preferred (foundation metadata concept)
A solid single-dose form that is soft or flexible and prepared by moulding of mixtures containing natural or synthetic polymers or gums. Preferred (foundation metadata concept)
A solid single-dose form usually prepared by moulding consisting of active substance(s) dispersed or dissolved in a suitable basis that may be soluble or dispersible or may melt at body temperature. Preferred (foundation metadata concept)
A solid single-dose form with a gum-like consistency. Preferred (foundation metadata concept)
A solid single-dose preparation made by freeze-drying of a liquid or semi-solid preparation. Preferred (foundation metadata concept)
A solid single-dose preparation obtained by compressing uniform volumes of particulate solids or by extrusion or moulding. Tablets may be single layer tablets resulting from a single compression of particles and or multilayer tablets consisting of concentric or parallel layers obtained by successive compressions of particles of different composition. Preferred (foundation metadata concept)
A solid single-dose preparation of small size and round or oval in shape. Preferred (foundation metadata concept)
A solid, sterile single-dose form suitable for implantation that may be provided with an administration device. Implants are intended for release over an extended period of time. Preferred (foundation metadata concept)
A solid, sterile single-dose form suitable for insertion into a body cavity that may be provided with an administration device. Inserts are intended for release over an extended period of time. Preferred (foundation metadata concept)
A somatic dysfunction in which the innominate bone is rotated posteriorly around a transverse axis relative to the sacrum. The innominate moves more freely in posterior rotation and is restricted in anterior rotation. The anterior superior iliac spine (ASIS) is positioned superiorly and the posterior superior iliac spine (PSIS) is positioned inferiorly when compared to the contralateral landmarks. Preferred (foundation metadata concept)
A sore at urethral meatus Preferred (foundation metadata concept)
A sore at urethral meatus (finding) Preferred (foundation metadata concept)
A specialisation for the delivery of pharmacy services in a military setting. Preferred (foundation metadata concept)
A specialisation for the delivery of pharmacy services in the complex hospital setting. Preferred (foundation metadata concept)
A specialist physiotherapist for neurological conditions. Preferred (foundation metadata concept)
A specialist physiotherapist in cardiorespiratory conditions. Preferred (foundation metadata concept)
A specialist physiotherapist in musculoskeletal conditions. Preferred (foundation metadata concept)
A specialist service for the assessment and treatment of eating disorders that is provided by a range of health care professions. This service may consist of psychologists, dieticians, nutritionists, social workers, peer support workers, general practitioners, and paediatricians. Preferred (foundation metadata concept)
A speciality of medicine focused on restoring health and functional abilities after acute illness or injury. Preferred (foundation metadata concept)
A specific, singular event or a short period in which substance use leads to damage to an individual's physical or mental health or results in behaviour that causes physical or psychological harm to others. Health damage results from intoxication behaviours, direct or secondary toxic effects on body organs and system, or harmful method of substance intake. Harm to others encompasses any physical or mental harm directly attributable to the user's intoxicated behaviour. Preferred (foundation metadata concept)
A spectrum of congenital malformative disorders characterised by the co-occurrence of distal limb anomalies (usually bilateral cleft feet and/or hands) and renal defects (e.g. unilateral or bilateral agenesis), that can be associated with a variety of other anomalies such as those of genitourinary tract (genital anomalies, ureteral hypoplasias, vesicoureteral reflux), abdominal well defects, intestinal atresias, and lung malformations. Familial cases have been reported in which an autosomal recessive inheritance was suspected. Preferred (foundation metadata concept)
A spectrum of diseases with manifestation of overgrowth that results from somatic activating mutations in the phosphatidylinositol-3-kinase/AKT/mTOR pathway. Preferred (foundation metadata concept)
A split thickness skin graft processed through a skin mesher which makes apertures onto the graft, allowing it to expand to many times its size. Preferred (foundation metadata concept)
A spondyloarthritis associated predominately with inflammatory bowel diseases and less frequently with other intestinal disorders such Whipple disease, coeliac disease and bowel-associated dermatitis-arthritis syndrome. Preferred (foundation metadata concept)
A state of being wherein a person has difficulty fully meeting current and/or ongoing financial obligations and/or does not feel secure in their financial future. Preferred (foundation metadata concept)
A state of matter where particles conform to the shape of their container and expand to fill the container. Preferred (foundation metadata concept)
A state of matter where particles conform to the shape of their container and keep a constant volume independent of pressure (if temperature stable). Preferred (foundation metadata concept)
A state of matter where particles form a definite shape and support their own weight but have the ability to flow like a liquid when pressure is applied. Preferred (foundation metadata concept)
A state of matter where particles form a stable, definite shape that can only change by force (e.g. break, cut). Preferred (foundation metadata concept)
A state where someone is vocally restless, uneasy, or disturbed. This may manifest as raised volume, accelerated speech rate, repetition of phrases, or increased emotional tone. Preferred (foundation metadata concept)
A status of being neither employed nor unemployed for example students, the retired, carers and also those who are not in work or seeking work. Preferred (foundation metadata concept)
A status of immunisation which is suboptimal for a person. Preferred (foundation metadata concept)
A stent suture is used primarily in non-valved aqueous drainage devices to restrict fluid outflow, reducing excessive fluid drainage and hypotony. Preferred (foundation metadata concept)
A stent using a collagen derived noninflammatory gelatin material. Preferred (foundation metadata concept)
A stepdown or lower dependency care unit from cardiac intensive care. Preferred (foundation metadata concept)
A sterile implantable device intended to be used as an attachment for a resurfacing humeral head prosthesis joint to treat a disease-damaged (e.g., arthritic) shoulder joint. It consists of a metallic peg [e.g., titanium (Ti), cobalt-chrome (Co-Cr), stainless steel] inserted into the humeral head so that the prosthesis on the humeral articulating surface can be attached. Preferred (foundation metadata concept)
A sterile, battery-powered, electromechanical device assembly intended to compensate for impaired hearing by transmitting vibrations, from transduced sound waves, through the skull to the inner ear. It typically consists of a self-contained microphone, amplifier, and vibrator mounted on a titanium (Ti) post which is implanted into the skull, typically the mastoid bone, and protrudes through the skin. Sound waves are converted into electrical signals and sent to the vibrator, which transmits vibrations directly through bone to the inner ears for hearing. It is used to treat hearing impairment due to middle and/or outer ear obstructive pathologies or types of conductive hearing loss. Preferred (foundation metadata concept)
A sterile, flexible, single-lumen tube intended to be introduced into the trachea of a neonate for the administration of exogenous surfactant as part of pulmonary surfactant therapy. Preferred (foundation metadata concept)
A stressful unexpected event that occurs with little advance warning, such as illness of a family member, accident or job loss. Preferred (foundation metadata concept)
A string of characters that may be parsed and executed to perform a query. Preferred (foundation metadata concept)
A structurally abnormal heart condition, without symptoms of heart failure, that confers a high risk of progression to symptomatic heart failure. Preferred (foundation metadata concept)
A structure damaged by an external force Preferred (foundation metadata concept)
A structured approach to modify specific behaviours by identifying targets, setting measurable goals, and implementing strategies. It involves monitoring progress, making adjustments as needed, and ensuring the changes are sustained over time and in various contexts. Preferred (foundation metadata concept)
A structured therapeutic programme using meditation to develop awareness and acceptance of emotions, thoughts and physical sensations to reduce psychological distress and support and improve wellbeing. Preferred (foundation metadata concept)
A subdivision of inferior hypogastric plexus, maybe derived from it, that supplies nerves to the rectum Preferred (foundation metadata concept)
A subdivision of the enteric plexus that lies within the tunica muscularis of the intestinal tract Preferred (foundation metadata concept)
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with a treatment of an unrelated neoplastic or autoimmune disease with cytotoxic agents, like cyclophosphamid, platins, melphalan and others. The neoplastic cells typically harbour unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. It usually presents with multilineage dysplasia and cytopenias 5-10 years after exposure, with symptoms related to the degree of bone marrow failure and the corresponding cytopenia (fatigue, bleeding and bruising, recurrent infections, bone pain). Preferred (foundation metadata concept)
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with treatment of an unrelated neoplastic disease with cytotoxic agents, like etoposide, doxorubicin, daunorubicin and others. The neoplastic cells often show rearrangements involving the mixed lineage leukaemia gene at 11q23. This subgroup of t-MN is typically associated with overt leukaemia, without preceding myelodysplastic syndrome, developing 2-3 years after exposure, presenting with non-specific symptoms related to ineffective haematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement. Preferred (foundation metadata concept)
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with treatment of an unrelated neoplastic disease with radiation. The neoplastic cells typically harbour unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. Patients frequently present with multilineage dysplasia and cytopenias 5-10 years after exposure. Preferred (foundation metadata concept)
A substance capable of combining with a specific receptor on a cell and initiating the same reaction or activity typically produced by the binding endogenous substance Preferred (foundation metadata concept)
A substance containing enzymes, mainly amylase, lipase, and protease, obtained from the pancreas of the hog or of the ox. It is a cream-coloured, amorphous powder, having a faint, characteristic, but not offensive odour. Its greatest activities are in neutral or faintly alkaline media; more than traces of mineral acids or large amounts of alkali hydroxides make it inert. An excess of alkali carbonate also inhibits its action. Pancreatin contains, in each mg, not less than 25 USP units of amylase activity, not less than 2 USP units of lipase activity, and not less than 25 USP units of protease activity. Pancreatin of a higher digestive power may be labelled as a whole-number multiple of the 3 minimum activities, or may be diluted with lactose, or with sucrose containing not more than 3.25% of starch, or with pancreatin of lower digestive power. Preferred (foundation metadata concept)
A substance containing enzymes, mainly lipase, with amylase and protease, obtained from the pancreas of the hog. It is a cream-coloured, amorphous powder having a faint characteristic, but not offensive odour. Its greatest activities are in neutral or faintly alkaline media; more than traces of mineral acids or large amounts of alkali hydroxides make it inert. An excess of alkali carbonate also inhibits its action. Pancrelipase contains, in each mg, not less than 24 USP units of lipase activity, not less than 100 USP units of amylase activity, and not less than 100 USP units of protease activity. Preferred (foundation metadata concept)
A substance product produced by living cells that circulates in body fluids (as blood) or sap and produces a specific effect on the activity of cells usually remote from its point of origin Preferred (foundation metadata concept)
A substance such as a detergent that, when added to a liquid, reduces its surface tension, thereby increasing its spreading and wetting properties Preferred (foundation metadata concept)
A substance that acts within the body to reduce the physiological activity of another chemical substance. Preferred (foundation metadata concept)
A substance that alters biochemical processes in a cell by decreasing or increasing the activity of an enzyme. Preferred (foundation metadata concept)
A substance that can disturb the development of an embryo or fetus and cause a birth defect in the child or halt the pregnancy outright Preferred (foundation metadata concept)
A substance that causes irritation specifically tending to produce inflammation Preferred (foundation metadata concept)
A substance that competes with, replaces or inhibits a specific metabolite of a cell and thereby interferes with the cell's normal metabolic functioning. Preferred (foundation metadata concept)
A substance that destroys or impairs the function of living cells Preferred (foundation metadata concept)
A substance that forms a complex with metal ions or other substrates Preferred (foundation metadata concept)
A substance that increases the risk of neoplasms in humans or animals either by directly affecting DNA or inducing neoplasms by other mechanisms Preferred (foundation metadata concept)
A substance that is produced by a living organism and is toxic, noxious, or poisonous. Preferred (foundation metadata concept)
A substance that modifies the immune response or the functioning of the immune system. Preferred (foundation metadata concept)
A subtype of Autosomal dominant Charcot-Marie-Tooth disease type 2 characterised by the childhood onset of distal weakness and areflexia (with earlier and more severe involvement of the lower extremities), reduced sensory modalities (primarily pain and temperature sensation), foot deformities, postural tremor, scoliosis and contractures. Optic atrophy, vocal cord palsy with dysphonia, sensorineural hearing loss, spinal cord abnormalities and hydrocephalus have also been reported. Preferred (foundation metadata concept)
A subtype of Charcot-Marie-Tooth disease type 4 characterised by childhood onset of severe, progressive, demyelinating sensorimotor neuropathy manifesting with distal muscle weakness and atrophy of hands and feet, distal sensory impairment (vibration and pinprick) of lower limbs, lactic acidosis, areflexia and severely reduced motor nerve conduction velocities (25 m/s or less). Patients may also present kyphoscoliosis, nystagmus, hearing loss, cerebellar ataxia and/or brain MRI abnormalities (putaminal and periaqueductal lesions). Preferred (foundation metadata concept)
A subtype of Waardenburg syndrome (WS) with characteristics of congenital deafness, minor defects in structures arising from neural crest resulting in pigmentation anomalies of eyes, hair, and skin, in combination with dystopia canthorum. Caused by a heterozygous mutation in the paired box-containing PAX3 gene on chromosome 2q36.1. In the majority of cases, WS1 is transmitted as an autosomal dominant disorder with a large variable inter and intrafamilial expressivity. Some affected patients present with a de novo mutation. Preferred (foundation metadata concept)
A subtype of acute myeloid leukaemia with recurrent genetic abnormalities characterised by clonal proliferation of myeloid blasts in the bone marrow, blood and, rarely, other tissues. Bone marrow typically shows small, hypolobated megakaryocytes and multilineage dysplasia. Patients typically present with leukocytosis, anaemia, variable platelet counts and a variety of nonspecific symptoms related to ineffective haematopoesis (fatigue, bleeding, bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly). High resistance to conventional chemotherapy is reported. Preferred (foundation metadata concept)
A subtype of acute myeloid leukaemia with recurrent genetic abnormalities characterised by leukocytosis, thrombocytosis and nonspecific symptoms related to ineffective haematopoiesis (fatigue, bleeding and bruising, recurrent infections, bone pain), with frequent extramedullary involvement typically presenting as gingival hyperplasia and lymphadenopathy. The disease is characterised by clonal proliferation of myeloid blasts harbouring mutations of the NPM1 gene in the bone marrow, blood and other tissues. It is associated with multilineage dysplasia, involving the myeloid, monocytic, erythroid, and megakaryocytic cell lineages. Preferred (foundation metadata concept)
A subtype of acute myeloid leukaemia with recurrent genetic abnormalities, characterised by clonal proliferation of myeloid blasts harbouring somatic mutations of the CEBPA gene in the bone marrow, blood and, rarely, other tissues. It can present with anaemia, thrombocytopenia, and other nonspecific symptoms related to ineffective haematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly). Preferred (foundation metadata concept)
A subtype of autosomal dominant Charcot-Marie-Tooth disease type 2, characterised by late adult-onset (50-60 years of age) of slowly progressive, axonal, peripheral sensorimotor neuropathy resulting in distal upper limb and proximal and distal lower limb muscle weakness and atrophy, in conjunction with distal, panmodal sensory impairment in upper and lower limbs. Tendon reflexes are reduced and nerve conduction velocities range from reduced to absent. Neuropathic pain has also been associated. Preferred (foundation metadata concept)
A subtype of autosomal dominant limb-girdle muscular dystrophy characterised by an adult-onset of slowly progressive, proximal pelvic girdle weakness, with none, or only minimal, shoulder girdle involvement, and absence of cardiac and respiratory symptoms. Mild to moderate elevated creatine kinase serum levels and gait abnormalities are frequently observed. Preferred (foundation metadata concept)
A subtype of autosomal recessive intermediate Charcot-Marie-Tooth (CMT) disease characterised by severe, early childhood-onset CMT neuropathy with prominent pes equinovarus deformity and impairment of hand muscles. Nerve conduction velocities usually range between 25-35 m/s and both axonal and demyelinating changes are observed on peripheral nerve pathology. Preferred (foundation metadata concept)
A subtype of autosomal recessive limb girdle muscular dystrophy characterised by a childhood to adolescent onset of progressive pelvic- and shoulder-girdle muscle weakness, particularly affecting the pelvic girdle (adductors and flexors of hip). Usually the knees are the earliest and most affected muscles. In advanced stages, involvement of the shoulder girdle (resulting in scapular winging) and the distal muscle groups are observed. Calf hypertrophy, cardiomyopathy, respiratory impairment, tendon contractures, scoliosis, and exercise-induced myoglobinuria may be observed. Preferred (foundation metadata concept)
A subtype of autosomal recessive limb girdle muscular dystrophy characterised by a variable age of onset of progressive, typically symmetrical and selective weakness and atrophy of proximal shoulder- and pelvic-girdle muscles (gluteus maximus, thigh adductors, and muscles of the posterior compartment of the limbs are most commonly affected) without cardiac or facial involvement. Clinical manifestations include exercise intolerance, a waddling gait, scapular winging and calf pseudo-hypertrophy. Preferred (foundation metadata concept)
A subtype of autosomal recessive limb-girdle muscular dystrophy characterised by a childhood onset of progressive shoulder and pelvic girdle muscle weakness and atrophy frequently associated with calf hypertrophy, diaphragmatic weakness, and/or variable cardiac abnormalities. Mild to moderate elevated serum creatine kinase levels and positive Gowers sign are reported. Preferred (foundation metadata concept)
A subtype of autosomal recessive limb-girdle muscular dystrophy characterised by a variable age of onset of progressive weakness and wasting of the proximal skeletal muscles of the shoulder and pelvic girdles, frequently associated with progressive respiratory muscle impairment and cardiomyopathy. Calf hypertrophy, muscle cramps and elevated serum creatine kinase levels are also observed. Neuro-psychomotor development is usually normal. Preferred (foundation metadata concept)
A subtype of autosomal recessive limb-girdle muscular dystrophy characterised by an onset in late adolescence or early adulthood of slowly progressive, proximal weakness and atrophy of shoulder and pelvic girdle muscles. Cardiac and respiratory muscles are not involved. Hypertrophy of the calf muscles and highly elevated serum creatine kinase levels are frequently observed. Preferred (foundation metadata concept)
A subtype of autosomal recessive limb-girdle muscular dystrophy characterised by childhood onset of progressive proximal weakness of the shoulder and pelvic girdle muscles, resulting in difficulty walking, scapular winging, calf hypertrophy and contractures of the Achilles tendon, which lead to a tiptoe gait pattern. Cardiac and respiratory involvement is rare. Preferred (foundation metadata concept)
A subtype of molybdenum cofactor deficiency caused by GPHN gene mutation. Preferred (foundation metadata concept)
A subtype of non-spastic cerebral palsy with involuntary, uncontrolled recurring, and occasionally stereotyped movements with a varying muscle tone; primitive reflex patterns predominate. Preferred (foundation metadata concept)
A subtype of non-spastic cerebral palsy with loss of muscular coordination with abnormal force and rhythm, and impairment of accuracy; commonly presents with gait and trunk ataxia, poor balance, past pointing, terminal intention tremor, scanning speech, nystagmus and other abnormal eye movements, and hypotonia. Low tone is a prominent feature. Preferred (foundation metadata concept)
A sudden onset, interruption of ongoing activities, a blank stare, possibly a brief upward deviation of the eyes. Usually, the patient will be unresponsive when spoken to. Duration is a few seconds to half a minute with very rapid recovery. An EEG (electroencephalogram) shows generalised spike-wave discharges during the event. A seizure originating at some point within, and rapidly engaging, bilaterally distributed networks. Preferred (foundation metadata concept)
A sudden pain, usually sharp, occurring during movement, or exacerbated by movement, and prompting cessation of movement Preferred (foundation metadata concept)
A sudden paroxysm of a predominant arrest (pause) of activities, freezing and immobilisation with electrographic correlate, that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of abnormal motor and/or non-motor phenomenon with electrographic correlate that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of abnormal motor and/or non-motor phenomenon with electrographic correlate, or a neonatal electrographic-only seizure (without clinical correlate) that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of abnormal motor and/or non-motor phenomenon with or without electrographic correlate, or a neonatal electrographic-only seizure (without clinical correlate) that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of abnormal motor, non-motor or electrographic-only phenomenon occurring in sequence within a single seizure. No predominant feature can be determined instead the seizure presents with a variety of clinical signs. Preferred (foundation metadata concept)
A sudden paroxysm of abnormal predominantly motor phenomenon with electrographic correlate that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of abnormal predominantly non-motor phenomenon with electrographic correlate that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of brief (less than 100 milliseconds) involuntary single or multiple contraction(s) of muscles(s) or muscle groups of variable topography (axial, proximal limb, distal) with electrographic correlate, that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of distinct alteration of autonomic nervous system function involving cardiovascular, pupillary, gastrointestinal, sudomotor (sweating), vasomotor, or thermoregulatory functions with electrographic correlate, that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of flexion, extension, or mixed extension-flexion of predominantly proximal and truncal muscles, with electrographic correlate, that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of predominant automatisms, defined as more or less coordinated motor activity with electrographic correlate, that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of regularly repetitive jerking of the same muscle groups which is either symmetric or asymmetric with electrographic correlate, that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A sudden paroxysm of sustained increase in muscle contraction lasting a few seconds to minutes, with electrographic correlate, that occurs during the period from birth until 44 weeks postmenstrual age. Preferred (foundation metadata concept)
A supernumerary tooth located near the midline of the dental arch between two central incisors. Preferred (foundation metadata concept)

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